Postnatal Cortical Development in Congenital Auditory Deprivation
نویسندگان
چکیده
منابع مشابه
Postnatal cortical development in congenital auditory deprivation.
The study investigates early postnatal development of local field potentials (LFPs) in the primary auditory cortex of hearing and congenitally deaf cats. In hearing cats, LFPs elicited by electrical intracochlear stimulation demonstrated developmental changes in mid-latency range, including reductions in peak and onset latencies of individual waves and a maturation of their shape and latencies ...
متن کاملCochlear implants: cortical plasticity in congenital deprivation.
Congenital auditory deprivation (deafness) leads to a dysfunctional intrinsic cortical microcircuitry. This chapter reviews these deficits with a particular emphasis on layer-specific activity within the primary auditory cortex. Evidence for a delay in activation of supragranular layers and reduction in activity in infragranular layers is discussed. Such deficits indicate the incompetence of th...
متن کاملErratum to “Development of Brainstem-Evoked Responses in Congenital Auditory Deprivation”
To compare the development of the auditory system in hearing and completely acoustically deprived animals, naive congenitally deaf white cats (CDCs) and hearing controls (HCs) were investigated at different developmental stages from birth till adulthood. The CDCs had no hearing experience before the acute experiment. In both groups of animals, responses to cochlear implant stimulation were acut...
متن کاملHearing after congenital deafness: central auditory plasticity and sensory deprivation.
The congenitally deaf cat suffers from a degeneration of the inner ear. The organ of Corti bears no hair cells, yet the auditory afferents are preserved. Since these animals have no auditory experience, they were used as a model for congenital deafness. Kittens were equipped with a cochlear implant at different ages and electro-stimulated over a period of 2.0-5.5 months using a monopolar single...
متن کاملCongenital auditory deprivation reduces synaptic activity within the auditory cortex in a layer-specific manner.
The present study investigates the functional deficits of naive auditory cortices in adult congenitally deaf cats. For this purpose, their auditory system was stimulated electrically using cochlear implants. Synaptic currents in cortical layers were revealed using current source density analyses. They were compared with synaptic currents found in electrically stimulated hearing cats. The naive ...
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ژورنال
عنوان ژورنال: Cerebral Cortex
سال: 2004
ISSN: 1460-2199,1047-3211
DOI: 10.1093/cercor/bhh156